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Dr. Karl R.O.S. Johnson's Chronic Condition Natural Treatment Blog

Intentional musings of a unique Shelby Township Michigan Chiropractic Physician dedicated to helping people find solutions to improving their health by rooting out causes to chronic conditions such as fibromyalgia, stubborn thyroid disorder symptoms, balance disorders, chronic knee & shoulder pain, migraines, sciatica, ADD/ADHD/ASD, back pain, peripheral neuropathy, gluten sensitivity and autoimmune disorders so they can Reclaim Their Life!

From the Desk of Dr. Karl R.O.S. Johnson, DC.....

Activate Your Vagus Nerve to Improve Immune Function and Health

Posted by Dr. Karl R.O.S. Johnson, DC on Wed, Jul 17, 2024

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What is the vagus Nerve?

The vagus nerve, known as the 10th cranial nerve, is a vital component of our autonomic nervous system. Responsible for rest and repair functions within our body's intricate neural network, this parasympathetic nerve emerges from the brainstem above the spinal cord alongside the other 11 cranial nerves. Its role in maintaining balance and regulating various bodily functions is crucial for overall well-being.

Cervical Vagus Nerve Animation_MOA_v2The cranial nerves are essential components of our body, playing a crucial role in transmitting sensory information, such as the sense of smell through the first cranial nerve to the brain's olfactory region. The trigeminal nerve, also known as the fifth cranial nerve, branches out to supply sensations to the face, head, and mucous membranes, while also providing motor impulses for chewing. This nerve is responsible for providing sensation to areas like your teeth, jaw, and face. During a dental visit, when numbing is administered before a procedure, a branch of this important nerve is anesthetized.

An intriguing fact about the vagus nerve is its unique journey from your head all the way down to your intestines, making it the only nerve to venture outside of the cranial region. This long and intricate nerve, among the 12 pairs of cranial nerves, has a significant impact on various parts of the body, including the brain, neck, torso, tongue, pharynx, heart, and gastrointestinal system. With sensory, special sensory, motor, and parasympathetic functions, the vagus nerve plays a vital role in regulating skin sensations, taste perception, muscle movements, and smooth muscle activity in vital organs like the trachea, bronchi, and gastrointestinal tract. The vagus nerve also plays a vital role in reducing inflammation and enhancing immune function.

The Vital Connection Between the Vagus Nerve and the Immune System

When considering our immune system, the vagus nerve often takes a back seat in our thoughts. Yet, the intricate connection between these two systems is vital, with the vagus nerve playing a pivotal role in ensuring the proper functioning of our immune system. Optimal immune function is crucial for combating infections, maintaining balance within the body, known as homeostasis, and aiding in the healing process during times of injury or illness. 

The vagus nerve serves as a bridge between our brain and immune system, orchestrating a symphony of responses that keep our defenses strong and our bodies resilient. This neural pathway not only communicates information swiftly in the face of threats but also regulates key immune responses to maintain a delicate balance within our internal environment. By recognizing and harnessing the power of the vagus nerve, we can unlock the full potential of our immune system and pave the way for improved health and well-being.

In essence, the vagus nerve acts as a silent guardian, tirelessly working behind the scenes to ensure that our immune system functions optimally, ready to defend us against any challenges that come our way. Its influence is far-reaching, touching every aspect of our health and vitality.

The vital and ongoing exchange of information within the microbiota-gut-brain axis, facilitated by the vagus nerve, is crucial for preserving balance and harmony in the body.

Embracing the connection between the vagus nerve and immune health opens up a world of possibilities for enhancing our overall well-being and resilience in the face of adversity.

The Vagus Nerve and Immune Health

Studies have shown that the vagus nerve plays a crucial role in both the innate and adaptive components of the immune system. The innate immune responses act as the body's initial defense against harmful pathogens, while also triggering specific adaptive immune responses. Adaptive immunity involves specialized immune cells and antibodies that not only combat foreign invaders but also create a memory of these threats to launch a more efficient immune response in the future.

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The vagus nerve facilitates communication between organs like the thymus, spleen, and lymph nodes. It also helps regulate cytokine production—proteins secreted by cells when attacked by pathogens or foreign bodies. By doing so, the vagus nerve helps control inflammation throughout the body, which positively affects overall immunity.

Within this discussion, we will explore these connections and reveal effective tactics for leveraging the vagus nerve's influence to bolster immune function.

Exploring the Vagus Nerve's Impact on Immune Function

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Mechanisms of Immune Regulation

Recent studies have unveiled a complex and crucial link between this key nerve and our immune system, shedding light on the intricate ways in which the vagus nerve influences our body's defense mechanisms. Through its communication network with the immune system, the vagus nerve enables rapid responses to threats, ensuring a delicate balance between protection and regulation. This newly discovered connection emphasizes the importance of understanding and harnessing the vagus nerve's impact on immune function for overall well-being and health.

Communication

The vagus nerve serves as a vital messenger within the immune system, enabling swift responses to threats like infections or injuries. This intricate communication network ensures balance, even in the face of stress or pathogenic invaders. Moreover, it acts as a bridge between the brain and immune system, transmitting crucial information to the amygdala for emotional processing. By enhancing our ability to cope with stress, this mechanism aids in averting detrimental inflammation and adverse effects linked to chronic stress.

Regulation of Cytokine Production

The vagus nerve also plays a crucial role in regulating cytokine production, which are vital chemical messengers made by specific immune and non-immune cells. These proteins serve as alarms when cells are under attack by pathogens or foreign invaders, prompting the immune system to mount a suitable response. However, an excess of cytokines can lead to widespread inflammation, highlighting the importance of controlling their levels. The vagus nerve steps in by transmitting signals that curb cytokine release, preventing exaggerated inflammation and fostering overall well-being.

As a study explains: "Cytokine synthesis and release is an essential component of the innate immune system, but inappropriate, excessive production results in a generalized systemic inflammatory response which damages distant organs. Recent research has identified an immunomodulatory function of the vagus nerve whereby activation of the efferent arm results in regulation of cytokine production. Termed the 'cholinergic anti-inflammatory pathway', this neuro-immune communication provides the host with a fast, discrete, and localized means of controlling the immune response and preventing excessive inflammation."

Enhancing Natural Killer (NK) Cell Function

Research indicates that stimulating the vagus nerve is associated with boosting the activity of natural killer (NK) cells, a vital type of white blood cell essential for immunity. These NK cells have the remarkable ability to identify and eliminate harmful pathogens or cancerous cells before they can pose a threat to the body.

EXPLORING THE BENEFITS OF VAGUS NERVE STIMULATION

Delving into the untapped potential of the vagus nerve for immune health propels us towards uncovering innovative strategies to maximize its influence.

An increasingly favored technique for enhancing vagus nerve activity is vagus nerve stimulation (VNS), where electrical signals are directed towards the nerve to prompt a physiological reaction. There are studies demonstrating the potential of VNS to alleviate inflammation and enhance emotional well-being and overall quality of life for individuals battling chronic conditions like rheumatoid arthritis or multiple sclerosis and lupus.

VNS procedures can be conducted using either surgical or non-invasive techniques. The surgical method entails the placement of stimulating wires around the vagus nerve in the neck, accompanied by the implantation of a signal generator in the chest (just below the left collarbone) to directly activate the vagus nerve in the neck.Non-invasive VNS utilizes an external device for nerve stimulation. Both methods have been recognized as safe and effective in relieving symptoms of long-term conditions like epilepsy and migraine headaches.

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Photo credit: Hellerhoff, CC BY-SA 4.0 <https://creativecommons.org/licenses/by-sa/4.0>, via Wikimedia Commons

While non-invasive VNS offers a convenient and less intrusive option, for individuals facing severe medical conditions such as epilepsy, gastroparesis, or treatment-resistant depression, surgical VNS may be the preferred course of action.

Non-Invasive Vagus Nerve Stimulation

An efficient and non-invasive method to activate the vagus nerve is through the use of a transcutaneous electrical vagus nerve stimulation device like gammaCore Sapphire™ by electroCore. This portable device is designed to target the vagus nerve in the neck region, allowing for convenient use at home, in the workplace, or wherever you may need it.

1024px-PavillonOreilleDroiteWith approximately 160,000 nerve fibers running along the carotid artery in the neck, compared to only about 960 fibers in the concha of the ear, targeting the vagus nerve in the neck proves to be the optimal pathway for non-invasive stimulation. The rich network of nerve fibers in the neck region allows for a more direct and efficient connection to the vagus nerve, ensuring that the stimulation reaches its intended target with precision and effectiveness. This strategic approach maximizes the potential benefits of vagus nerve activation, offering a comprehensive and reliable method for enhancing immune function and overall well-being. By prioritizing the neck as the primary site for stimulation, we can harness the full power of the vagus nerve to promote health and vitality in a seamless and impactful manner. Number 1 in the photo of the right ear is where the concha is located. Photo credit: Didier Descouens, CC BY-SA 3.0 <https://creativecommons.org/licenses/by-sa/3.0>, via Wikimedia Commons), 

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In the photo above, the correct location and positioning of the gammaCore Sapphire™ is shown to stimulate the vagus nerve in the neck. The vagus nerve is located within the carotid sheath which is consisting of a supportive soft tissue framework that encases the common carotid artery, the jugular vein, and the vagus nerve, along with various other cranial nerves and lymph nodes.

gammaCore Sapphire™

The gammaCore Sapphire™ is a cutting-edge device meticulously crafted to target the vagus nerve as it winds its way through the neck region. With a sophisticated design that incorporates a patented wavelength frequency and a true sinewave signal for stimulation, this device ensures a seamless and comfortable user experience. Its electrical output is intricately calibrated to steer clear of nerve fibers that could potentially trigger a bradycardia response, safeguarding against adverse effects and maximizing safety and efficacy. By prioritizing precision and safety in its design, the gammaCore Sapphire™ stands out as a reliable and innovative tool for enhancing immune function and overall well-being.

gammaCoreTM Sapphire Deivce Images

ALTERNATIVE METHODS FOR ACTIVATING THE VAGUS NERVE

DIETARY APPROACHES

Including probiotics and prebiotics in your diet can have a positive impact on the vagus nerve, stimulating its activity. Probiotics, live bacteria found in fermented foods like yogurt, and prebiotics, dietary fibers that nourish beneficial gut bacteria, work together to support vagus nerve health and enhance overall immune function. Embracing these foods in your daily meals can contribute to a healthier and more robust immune system.

BREATHWORK STRATEGIES

Deep breathing exercises are an accessible way to stimulate the vagus nerve. Taking slow, deep breaths activates the parasympathetic nervous system—the part responsible for relaxation—sending signals to the vagus nerve and encouraging it to fire more frequently. Common methods are box breathing and 4-7-8 breathing.

YOGA POSES FOR VAGUS NERVE STIMULATION

Practicing yoga poses like the serene corpse pose (savasana) and empowering shoulder stand (sarvangasana) can be incredibly effective in activating the vagus nerve. These gentle postures not only induce relaxation in the body but also serve as a signal booster for the vagus nerve, intensifying its activity and enhancing overall immune function.

COLD IMMERSION

Engaging in cold water immersion or indulging in refreshing cold showers can ignite the activation of the vagus nerve, aiding in the reduction of inflammation.

Acupuncture and Massage

Ancient practices like acupuncture and soothing massage therapy have the potential to activate the vagus nerve, helping to alleviate inflammation and reduce stress levels within the body.

Discover a helpful infographic showcasing additional vagus nerve stimulating activities that can easily be done from the comfort of your own home. Simply click here to access valuable techniques for enhancing your immune health.

BENEFITS OF STIMULATING THE VAGUS NERVE

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INFLAMMATION CONTROL

Activation of the vagus nerve has shown promise in controlling inflammatory responses within the body. Research indicates that stimulating this crucial nerve may offer therapeutic benefits for conditions such as arthritis and chronic pain, by effectively managing inflammatory processes.

Autoimmunity Modulation

Activating the vagus nerve can play a crucial role in modulating autoimmune responses, offering valuable support to individuals dealing with autoimmune conditions.

Irritable Bowel Disease (IBD)

The vagus nerve has the potential to impact irritable bowel disease, often associated with a compromised immune system. By stimulating this nerve, it can help alleviate intestinal inflammation and enhance gut health, offering a promising avenue for treating IBD.

EMOTIONAL WELL-BEING

The vagus nerve contributes to mood regulation, aiding in stress and anxiety reduction. Activation of this nerve can alleviate symptoms of depression, especially in severe instances, and is FDA-approved for treating treatment-resistant depression.

IMPACT OF LIFESTYLE CHOICES ON VAGUS NERVE ACTIVITY AND IMMUNE WELLNESS

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Sleep

Prioritizing quality sleep each night is crucial for maintaining the optimal function of your vagus nerve and supporting overall well-being. Aim for a solid 7-9 hours of restorative sleep to ensure that your body and mind can recharge effectively. During sleep, your vagus nerve gets the opportunity to reset and recalibrate, promoting immune function, reducing inflammation, and enhancing emotional well-being. By making sleep a priority in your daily routine, you are not only taking care of your vagus nerve but also setting the foundation for a healthier and more vibrant life. So, create a peaceful bedtime routine, optimize your sleep environment, and embrace the rejuvenating power of a good night's rest for a thriving immune system and overall wellness.

Stress Management

Engaging in stress-relieving practices like deep breathing, meditation, mindfulness, yoga, or other physical activities can help maintain optimal function of the vagus nerve. These activities not only aid in reducing stress levels but also promote overall relaxation and well-being. By incorporating these practices into your daily routine, you can effectively support the health of your vagus nerve, enhancing its ability to regulate inflammation, modulate autoimmune responses, and contribute to emotional stability. Embracing these holistic approaches to stress management can have a profound impact on your immune system and overall health, fostering a sense of balance and vitality in both body and mind. So, take time for yourself each day to engage in these rejuvenating practices and nurture your vagus nerve for a healthier and more resilient immune system.

NUTRITIONAL STRATEGIES

Incorporating a diverse array of nutrient-rich foods into your daily meals not only provides essential nourishment for your body but also plays a vital role in supporting the health of your vagus nerve and immune system. Fruits and vegetables offer a plethora of vitamins, minerals, and antioxidants that help bolster immune function and promote overall well-being. Whole grains provide a steady source of energy and fiber, aiding in digestive health and contributing to a balanced gut microbiome, which is closely linked to vagus nerve activity. Lean proteins supply the building blocks for cellular repair and maintenance, while healthy fats, such as those found in nuts, seeds, and oily fish, support brain health and nerve function. By embracing a well-rounded diet filled with a variety of nutritious foods, you are not only fueling your body but also nurturing the intricate connection between your vagus nerve, immune system, and overall health.

PHYSICAL ACTIVITY

Regular physical activity not only enhances vagal tone and heart rate variability but also plays a crucial role in strengthening the mind-body connection. By incorporating at least 30 minutes of moderate exercise into your daily routine, you are not just improving your physical health but also boosting your mental well-being. Physical activity has been shown to release endorphins, the body's natural feel-good chemicals, which can help reduce stress, anxiety, and depression. Additionally, exercise promotes better sleep quality, increased energy levels, and improved cognitive function. So, lace up your sneakers, hit the gym, go for a run, or take a dance class – whatever activity you enjoy, make it a priority to move your body and reap the countless benefits for both your physical and mental health. Your vagus nerve will thank you for it, as you support its function in regulating inflammation and enhancing immune wellness through regular exercise.

SUMMARIZING THE CRUCIAL FACTORS FOR OPTIMAL VAGUS NERVE HEALTH

By prioritizing activities that promote the health of your vagus nerve, such as ensuring you get a solid 7-9 hours of restorative sleep each night, practicing effective stress management techniques like deep breathing, meditation, or yoga, consuming a well-rounded diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats, and engaging in regular physical activity for at least 30 minutes a day, you can actively support your immune system, optimize your vagal tone and heart rate variability, and ultimately enhance your overall well-being. These lifestyle choices not only contribute to the health of your vagus nerve but also play a significant role in regulating inflammation, modulating autoimmune responses, and promoting emotional well-being. By incorporating these habits into your daily routine, you can empower your body's natural defenses, improve your quality of life, and take proactive steps towards long-term health and vitality.

CONCLUSION: UNLEASHING THE POWER OF THE VAGUS NERVE FOR IMMUNE SYSTEM SUPPORT

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Understanding the intricate connection between the vagus nerve and the immune system not only empowers us to lead a vibrant and balanced lifestyle but also highlights the importance of seeking professional guidance when dealing with severe or chronic conditions. It is essential to prioritize consulting with your healthcare provider before implementing any new health practices to ensure that they are safe and effective for your specific needs. By collaborating with healthcare professionals, you can tailor your approach to optimizing vagus nerve function and immune health, ultimately paving the way for a healthier and more resilient future.

For those eager to delve deeper into the world of non-invasive vagus nerve stimulation, take a closer look at the clinical trials showcasing the effectiveness of gammaCore Sapphire™ by electroCore. Start exploring today to unlock the potential benefits for your immune system and overall well-being.

To experience the transformative benefits of the gammaCore Sapphire™, simply fill out the form below and embark on your journey towards enhanced immune support and overall well-being.

Always remember one of my mantras., "The more you know about how your body works, the better you can take care of yourself."


For more details about the natural approach I take with my patients, take a look at the book I wrote entitled: Reclaim Your Life; Your Guide To Revealing Your Body's Life-Changing Secrets For Renewed Health. It is available in my office or at Amazon and many other book outlets. If you found value in this article, please use the social sharing icons at the top of this post and please share with those you know who are still suffering with chronic health challenges, despite receiving medical management. Help me reach more people so they may regain their zest for living! Thank you!

ALL THE BEST – DR. KARL R.O.S. JOHNSON, DC – DIGGING DEEPER TO FIND SOLUTIONS 

References:

Thayer JF, Sternberg EM. Neural aspects of immunomodulation: focus on the vagus nerve. Brain Behav Immun. 2010 Nov;24(8):1223-8. doi: 10.1016/j.bbi.2010.07.247. Epub 2010 Jul 30. PMID: 20674737; PMCID: PMC2949498.

Wachsmuth HR, Weninger SN, Duca FA. Role of the gut-brain axis in energy and glucose metabolism. Exp Mol Med. 2022 Apr;54(4):377-392. doi: 10.1038/s12276-021-00677-w. Epub 2022 Apr 26. PMID: 35474341; PMCID: PMC9076644.

Matteoli G, Boeckxstaens GE,The vagal innervation of the gut and immune homeostasis, Gut 2013;62:1214-1222.

Johnston GR, Webster NR. Cytokines and the immunomodulatory function of the vagus nerve. Br J Anaesth. 2009 Apr;102(4):453-62. doi: 10.1093/bja/aep037. Epub 2009 Mar 3. PMID: 19258380.

Wilkie L, Fisher Z, Kemp AH. The Complex Construct of Wellbeing and the Role of Vagal Function. Front Integr Neurosci. 2022 Jul 7;16:925664. doi: 10.3389/fnint.2022.925664. PMID: 35875509; PMCID: PMC9301262.

Breit S, Kupferberg A, Rogler G, Hasler G. Vagus Nerve as Modulator of the Brain-Gut Axis in Psychiatric and Inflammatory Disorders. Front Psychiatry. 2018 Mar 13;9:44. doi: 10.3389/fpsyt.2018.00044. PMID: 29593576; PMCID: PMC5859128.

Fonseca RC, Bassi GS, Brito CC, Rosa LB, David BA, Araújo AM, Nóbrega N, Diniz AB, Jesus ICG, Barcelos LS, Fontes MAP, Bonaventura D, Kanashiro A, Cunha TM, Guatimosim S, Cardoso VN, Fernandes SOA, Menezes GB, de Lartigue G, Oliveira AG. Vagus nerve regulates the phagocytic and secretory activity of resident macrophages in the liver. Brain Behav Immun. 2019 Oct;81:444-454. doi: 10.1016/j.bbi.2019.06.041. Epub 2019 Jul 2. PMID: 31271871; PMCID: PMC7826199.

Das UN. Can vagus nerve stimulation halt or ameliorate rheumatoid arthritis and lupus? Lipids Health Dis. 2011 Jan 24;10:19. doi: 10.1186/1476-511X-10-19. PMID: 21261967; PMCID: PMC3037330.

Gallowitsch-Puerta M, Pavlov VA. Neuro-immune interactions via the cholinergic anti-inflammatory pathway. Life Sci. 2007 May 30;80(24-25):2325-9. doi: 10.1016/j.lfs.2007.01.002. Epub 2007 Jan 13. PMID: 17289087; PMCID: PMC2921074.

O'Reardon JP, Cristancho P, Peshek AD. Vagus Nerve Stimulation (VNS) and Treatment of Depression: To the Brainstem and Beyond. Psychiatry (Edgmont). 2006 May;3(5):54-63. PMID: 21103178; PMCID: PMC2990624.

Topics: Immune System, depression, Anxiety, inflammation modulation, Vagus Nerve, non-invasive vagal nerve stimulation, nVNS, cranial nerves, immune modulation, gammaCore Sapphire, gammaCore

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