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Dr. Karl R.O.S. Johnson's Chronic Condition Natural Treatment Blog

Intentional musings of a unique Shelby Township Michigan Chiropractic Physician dedicated to helping people find solutions to improving their health by rooting out causes to chronic conditions such as fibromyalgia, stubborn thyroid disorder symptoms, balance disorders, chronic knee & shoulder pain, migraines, sciatica, ADD/ADHD/ASD, back pain, peripheral neuropathy, gluten sensitivity and autoimmune disorders so they can Reclaim Their Life!

From the Desk of Dr. Karl R.O.S. Johnson, DC.....

6 Factors Which Can Affect The Conversion of T4 to T3

Posted by Dr. Karl R.O.S. Johnson, DC on Tue, Sep 10, 2024

problems with conversion of INactive Thyroid Hormone T4 to active thyroid hormone t3 can cause symptoms and signs of hypothyroidism

Thyroid hormones play a crucial role in regulating your body's metabolism and is essential for brain development in infants. The thyroid hormones exist in two main forms: thyroxine, also known as T4, and triiodothyronine, or T3. T4, with its 4 iodine atoms, transforms into T3 when one iodine atom is removed, resulting in a potent hormone that drives cellular functions. This conversion mainly occurs in the liver and the gut.

T3 emerges as the dominant thyroid hormone, boasting 7-10 times more potency than its T4 counterpart. As T4 acts as the precursor thyroid hormone, paving the way for T3 to become the active thyroid hormone, a fascinating process unfolds when an "opposite mirror-image" iodine is detached from T4, giving rise to reverse T3, also known as RT3.

Reverse T3, or RT3, plays a fascinating role in the thyroid system by acting as a natural brake for the body's functions. While T3 typically fuels our bodily processes, there are instances, such as during critical illness, where it's beneficial for the body to curb its activities. Factors like stress, extreme dieting, low serum iron levels, cortisol deficiencies, and diabetes can trigger an uptick in RT3 production. This intricate mechanism showcases how the thyroid system delicately balances acceleration and deceleration to support overall health and well-being.

If individuals exhibit normal T4 levels alongside low or diminished T3 levels, it raises concerns about a potential thyroid hormone conversion issue. The thyroid gland primarily secretes thyroxine, also known as T4, with a smaller amount of triiodothyronine, or T3, being produced as well. The conversion of T4 to T3 accounts for the majority of T3 production. However, various factors can impact this conversion process, which will be explored further in this post.

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Topics: Hypothyroidism, T4, T3, thyroid hormones, stress, Low Thyroid Symptoms, Hypothyroidism Symptoms, Reverse T3, Stress Hormones, Unhealthy Gut, Healthy Gut, gut dysbiosis, Thyroid hormone conversion, Pro-Inflammatory Cytokines

The Thyroid-Gut Connection; Poor Thyroid Hormone Conversion

Posted by Dr. Karl R.O.S. Johnson, DC on Thu, Feb 28, 2013

Most of the patients I consult with have a few things in common:

  1. They were diagnosed with hypothyroidism at some point in their lives.
  2. They take some form of thyroid hormone replacement.
  3. They continue to experience some degree of thyroid symptoms despite conventional treatment.
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Topics: TSH, T3, hypothyroid, gut, hypothyroid symptoms, Reverse T3

Does High TSH with Normal T4 and T3 Mean Hypothyroidism?

Posted by Dr. Karl R.O.S. Johnson, DC on Tue, Feb 26, 2013

A research study published in December 2012 sheds some light on a phenomenon we see quite often …

A patient has elevated TSH but normal T4 and T3.

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Topics: TSH, insulin resistance, T4, T3, hypothyroid, pre-diabetes

Not Knowing If You Have Autoimmune Thyroid is Harmful To Your Health

Posted by Dr. Karl R.O.S. Johnson, DC on Tue, Feb 19, 2013

If you've been reading my blog for a while you know I have revealed the fact that the number-one cause of hypothyroidism is an autoimmune thyroid [1]. Based on the number of medically managed hypothyroid patients who have sought my care for their numerous persistant health challenges, thyroid hormone replacement alone does not address the underlying cause of Hashimoto's (autoimmune thyroid). Too many patients who only utilize thyroid hormone replacement therapy may never feel the way they truly desire. It's a shame and that's why I am dedicated to helping patient's with autoimmune thyroid improve their health with my unique blend of natural methods.

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Topics: Hypothyroidism, autoimmune, Hashimoto's, TSH, thyroid, autoimmune thyroid, T4, T3, Immune System, TH1, TH2, TPO Ab, TBG Ab

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